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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKC
All Species:
7.58
Human Site:
T22
Identified Species:
12.82
UniProt:
Q9UQB9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQB9
NP_001015878.1
309
35591
T22
P
A
G
E
E
L
A
T
A
N
Q
T
A
Q
Q
Chimpanzee
Pan troglodytes
XP_001142357
309
35587
T22
P
A
G
E
E
L
A
T
A
N
Q
T
A
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001098364
471
52859
A184
P
A
G
E
A
V
T
A
A
N
Q
T
A
Q
Q
Dog
Lupus familis
XP_849906
346
39574
K56
P
T
A
A
P
G
Q
K
V
V
E
N
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
O88445
282
32888
G19
T
I
N
D
F
E
I
G
R
P
L
G
R
G
K
Rat
Rattus norvegicus
O55099
343
39216
E59
V
P
G
Q
K
L
T
E
N
K
G
A
T
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
E20
E
A
P
C
Q
K
N
E
E
S
K
K
R
Q
W
Chicken
Gallus gallus
XP_425725
409
46456
N126
D
S
V
S
K
Q
K
N
E
E
S
T
K
K
K
Frog
Xenopus laevis
Q6GPL3
368
41997
D79
G
R
V
A
L
G
T
D
V
A
S
H
N
T
A
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
A32
E
M
N
P
D
T
H
A
V
S
G
P
G
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
V21
L
P
H
L
L
A
K
V
P
E
E
H
Q
E
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
T18
P
E
K
E
T
V
N
T
P
Q
K
G
G
K
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q683C9
282
32738
D18
Q
K
R
W
T
T
S
D
F
D
I
G
K
P
L
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
S83
S
P
I
R
K
A
T
S
S
K
M
I
H
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
63.4
70.5
N.A.
72.4
67.3
N.A.
64.7
52.3
58.1
65.3
N.A.
43.1
N.A.
54.6
N.A.
Protein Similarity:
100
100
64.7
78.9
N.A.
82.5
79.3
N.A.
78.3
62.3
71.1
78.7
N.A.
62.6
N.A.
68.9
N.A.
P-Site Identity:
100
100
73.3
6.6
N.A.
0
13.3
N.A.
13.3
6.6
0
0
N.A.
0
N.A.
20
N.A.
P-Site Similarity:
100
100
80
20
N.A.
13.3
26.6
N.A.
33.3
33.3
0
20
N.A.
13.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.3
38.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.8
55.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
29
8
15
8
15
15
15
22
8
0
8
22
8
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
8
0
0
15
0
8
0
0
0
0
0
% D
% Glu:
15
8
0
29
15
8
0
15
15
15
15
0
0
15
0
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
8
0
29
0
0
15
0
8
0
0
15
22
15
8
8
% G
% His:
0
0
8
0
0
0
8
0
0
0
0
15
8
0
0
% H
% Ile:
0
8
8
0
0
0
8
0
0
0
8
8
0
0
0
% I
% Lys:
0
8
8
0
22
8
15
8
0
15
15
8
15
15
15
% K
% Leu:
8
0
0
8
15
22
0
0
0
0
8
0
0
0
15
% L
% Met:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
15
8
8
22
0
8
8
0
8
% N
% Pro:
36
22
8
8
8
0
0
0
15
8
0
8
0
8
8
% P
% Gln:
8
0
0
8
8
8
8
0
0
8
22
0
8
29
22
% Q
% Arg:
0
8
8
8
0
0
0
0
8
0
0
0
15
8
0
% R
% Ser:
8
8
0
8
0
0
8
8
8
15
15
0
8
8
0
% S
% Thr:
8
8
0
0
15
15
29
22
0
0
0
29
8
8
0
% T
% Val:
8
0
15
0
0
15
0
8
22
8
0
0
0
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _